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Mechanisms of radiotherapy-associated cognitive disability in patients with brain tumours

Broad gene-mapping work led by Pickart and colleagues reported modulation of thousands of genes, with roughly a third of human gene patterns shifting toward expression states associated with younger or healthier tissue

48 , the histological technique entails the dissection of liver, heart, and pancreas tissue specimens, which are washed with saline, immersed in a fixative, and subsequently processed for histopathological and immunohistochemical analyses

Lactic acid is present as a lactate-conjugated base at a physiological pH of 7.4, and exists in two enantiomeric forms in mammals: L-lactate is produced during glycolysis when oxygen levels are low (3), while D-lactate is formed through the detoxification of methylglyoxal (2)

MedinaMAAndradeVMCaracciMOAvilaMEVerdugoDAVargasMFet al