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In vitro and in vivo results showed that ESIONPs@EXOs targeted and attenuated pathological angiogenesis by inducing ferroptosis and immunotherapeutic ability, while presenting an excellent T1-weighted contrast feature of MRI for retinal angiogenesis imaging

Studies using 1 H-MRS have found an increase in lactate in the cingulate gyrus, subcortical gray matter nuclei, corpus callosum, superior temporal gyrus, and pre- and post-central gyri, with this abnormality being more common in adults with ASD [186], while others have not found any increase in lactate in individuals with ASD [187]