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PubMed PMID: 18670186 Mitochondrial function Mitochondrial glutathione: features, regulation and role in disease

Daniel Cameron, MD, MPH Lyme disease clinician with over 30 years of experience and past president of ILADS

Worldwide systematic review of GSTM1 and GSTT1 null genotypes by continent, ethnicity, and therapeutic area

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The impaired cross-talk between dysfunctional endothelial cells and fibroblasts further compromises angiogenesis, as endothelial cells provide critical paracrine signals (such as PDGF-BB) that recruit and activate fibroblasts, while fibroblasts produce VEGF and deposit the ECM scaffold necessary for endothelial tube formation