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TGF-1 is researched for its role in cell proliferation, differentiation, and apoptosis

GH and IGF-1 can support cell growth

J Cardiothorac Vasc Anesth 2017

CT of the pelvis and lumbar spine were obtained, which showed numerous sclerotic lesions in the lower lumbar, pelvic, and bilateral femoral bones

Because of this dual action, tirzepatide may: Reduce appetite Improve insulin sensitivity Slow digestion Enhance metabolic regulation This broader hormonal activity may explain why some patients experience strong weight loss results with tirzepatide