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According to one human study out of Boston, upping fiber intake by 14 grams per day led to a 10 percent decrease in daily caloric intake and increased weight loss by four pounds over four months

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However, in a much larger randomized controlled trial of simvastatin and an antioxidant combination of 600 mg of all - rac --tocopherol (297 mg of RRR --tocopherol), 250 mg of vitamin C, and 20 mg of -carotene daily) in more than 20,000 men and women with CHD or diabetes mellitus, the antioxidant combination did not adversely affect the cardioprotective effects of simvastatin therapy over a five-year period (131)

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It has also been studied in a phase I trial (NCT02256631) in combination with VRC01 and another variant of VRC01, VRC07-532LS (ref