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B.MadderA

Oxidative stress (OS) is characterized by an imbalance between oxidation and anti-oxidation mechanisms (enzymic and non-enzymic antioxidants), leading to an increase in oxidation intermediates such as reactive oxygen species (ROS) (5)

Because no specific clinical or laboratory features of HRS have been identified, diagnosis depends on (1) the presence of severe liver disease, (2) a rise in creatinine to greater than 1.5 mg/dL (25.6 mol/L), (3) no evidence of other renal disease by urinalysis and clinical history, and (4) lack of improvement in renal function with treatments that increase intravascular volume (such as stopping diuretics, or administration of fluids and/or albumin)

Sesti G, Sciacqua A, Cardellini M, Marini MA, Maio R, Vatrano M, Succurro E, Lauro R, Federici M, Perticone F: Plasma concentration of IGF-I is independently associated with insulin sensitivity in subjects with different degrees of glucose tolerance

Argentina 9.4.2.1