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RA is more common in women, who have two to three times of risk to develop the disease comparing with men, and its incidence is on a noticeable upward trend (Wu et al., 2022), leading to a range of diseases, increased mortality risk ( Although the pathogenesis of RA remains unclear, studies have identified several contributing factors, including genetic susceptibility and environmental risk factors such as smoking (the strongest environmental risk factor for RA), exposure to dust, viral infections, obesity, low socioeconomic status, and gut microbiota alterations (Venetsanopoulou et al., 2022)

10.1007/s10725-016-0235-2 Plant Growth Regul

Elosta, A., Ghous, T

Also, a substantial decrease in glutathione levels precedes the mitochondrial dysfunction and neuronal death found in Parkinsons disease, suggesting GSH depletion may initiate the subsequent impairment.It also suggests that increasing GSH levels may have potential benefit toward preventing diseases associated with mitochondrial dysfunction

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