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DNA methylation of the imprinted suppressor gene p57/Kip2 that encodes an embryonic cyclin-dependant kinase has also been found in a high proportion (56%) of prostate cancer (Lodygin et al, 2005)

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This copy number increase likely occurred after the GST Americas sweep, as the GST Americas haplotype was rare in New Mexico while the copy number increase was observed in almost all individuals

This greatly encourages and promotes our enthusiasm for continued in-depth research in the vast field of digestive system disorders