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This innovation effectively reduces oxidative stress, inflammation, and fibrosis in the liver while promoting tissue repair

Importantly, HO-1 can be targeted pharmacologically by interventions that seek its upregulation or enhancement of its various arms of action, via: (1) induction of HO-1 expression with drugs such as heme arginate, (2) administration of CO by inhalation or use of CO releasing molecules (CORM), and (3) administration of biliverdin/bilirubin or use of inhibitors of bilirubin conjugation that would result in increased bilirubin levels

The stability of the investigated compounds was confirmed from the negative values obtained for their E HOMO and E LUMO [24]

Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer

The term "pharmaceutically acceptable salt" includes salts of the active compounds that are prepared with relatively nontoxic acids or bases, depending on the particular substituents found on the compounds described herein