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Emerging therapeutics and evolving assessment criteria for intracranial metastases in patients with oncogene-driven non-small-cell lung cancer

As neurosteroids, DHEA and DHEAS can bind directly to neurotransmitter receptors, and have been found to modulate neural activity by acting as noncompetitive antagonists at GABAA receptors, reducing inhibitory neurotransmission, and as positive allosteric modulators at NMDA receptors, enhancing excitatory signaling, and facilitating dendritic growth, axonal elongation, and synaptic plasticity in response to environmental stimuli (, )

Protein oxidative damage in the stratum corneum: Evidence for a link between environmental oxidants and the changing prevalence and nature of atopic dermatitis in Japan

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Its combined appetite-suppressant and energy-expenditure effects make it more effective than traditional GLP-1 monotherapies, offering a potential breakthrough in obesity treatment