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Allen BG, Bhatia SK, Anderson CM, Eichenberger-Gilmore JM, Sibenaller ZA, Mapuskar KA, Schoenfeld JD, Buatti JM, Spitz DR, Fath MA

As documented in the peer-reviewed literature, GSH serves as a cofactor for glutathione peroxidase (GPx) and glutathione S-transferase (GST), and plays a central role in cellular redox homeostasis (ncbi.nlm.nih.gov, pmc.ncbi.nlm.nih.gov)

The major consumer of intracellular NADPH is H 2 O 2 detoxification by glutathione peroxidases (GPX) and peroxiredoxin (PRX) and fatty-acid synthesis [18]