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Glucose-deprived conditions, rather than hypoxic conditions, may be a pivotal contributing factor for the death of cancer cells in the tumor microenvironment 5

Inability to self-administer the intranasal spray, except with assistance from a spouse or home care nurse

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Additionally, in clinical practice, resistance exercise with lower intensity and reduced energy expenditure may be a more feasible option than aerobic exercise for patients who are unable to tolerate aerobic exercise, which is a common situation

The samples were heated for 10 min at 95 C and then lysed with a Bioruptor for ten cycles of 30-s sonication and 30-s break on high performance