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The increase in adiposity has been associated with metabolic changes in MM cells, such as an increase in the metabolite acetyl-coA synthetase 2 (ACSS2) in MM cells, induced by adipocyte-secreted angiotensin II and driving MM growth in vitro and in vivo at least partly by enhancing the stability of the myeloma oncoprotein IRF4 (74)

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10.1038/sj.onc.1210638 41 De VosA.HeimbergH.QuartierE.HuypensP.BouwensL.PipeleersD.et al (1995)

News Release January 05, 2016 Cinnamon Spices and Supplements Found to Vary Widely in Levels of Potentially Helpful and Harmful Compounds Reports ConsumerLab.com White Plains, New York, January 5, 2016 Cinnamon supplements may be helpful for controlling blood sugar in people with type 2 diabetes or prediabetes, possibly due to compounds known as proanthocyanidins or PACs