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Description

A preliminary study demonstrated the feasibility of producing CD123-targeted CAR-T cells from the T cells of patients with IMIDs, as well as their in vitro cytotoxicity against circulating autologous pDCs (113)

[14] Clinical significance [edit] Specific mutations in the isocitrate dehydrogenase gene IDH1 have been found in several tumor types, [16] notably brain tumors including astrocytoma and oligodendroglioma