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Theoretical Long-Term Risks TB500 enhances angiogenesis and cellular proliferation, which has raised concerns primarily in preclinical models about: Accelerating growth of dormant tumors Disrupting immune surveillance Overstimulating wound healing in healthy tissues There is no conclusive evidence that TB500 causes cancer, but its role in cell migration warrants caution, especially at high doses or long-term use without breaks

It supports skin repair and regeneration

In clinical trials of ketorolac or another NSAID, heart failure, palpitations, pallor, sinus tachycardia, and syncope were reported in less than 1% of patients

M., Boltz, T., Francia, M., Bot, M., Ramesh, N

10.3109/10715762.2013.789136 Free Radic Res