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Sci Total Environ 662:7787 Naylor C, Rodrigues C (1995) Development of a test method for Chironomus riparius using a formulated sediment

121,122 However, some studies have demonstrated that glutamine supplementation protects against AKI and attenuates tubular apoptosis

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When present in the nucleus, these aggregates sequester transcription factors resulting in gene expression alterations (Labbadia and Morimoto, 2013), while when present in the cytosol, they may bind to diverse proteins resulting in an altered autophagy-lysosome pathway, reduced protein translation, synaptic dysfunction, reduced axonal transport, mitochondrial toxicity, and energy imbalance among others (Labbadia and Morimoto, 2013

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