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The "right" dose sits in a narrow window that depends on: Delivery method - injectable GHK-Cu vs topical GHK-Cu vs oral/sublingual GHK-Cu Goal - skin rejuvenation , hair and scalp support, wound healing , general anti-ageing Individual factors - age , skin type , baseline GHK levels , other peptides being stacked Natural plasma GHK falls from roughly 200 ng/ml at age 20 to around 80 ng/ml by age 60

[DOI] [PMC free article] [PubMed] [Google Scholar] 162.Peng X.P., Nie C., Guan W.Y., Qiao L.D., Lu L., Cao S.J

For reduction experiments BSO-OxOAc (2 mM) was dissolved in phosphate buffer (500 mM, pH 7.4)

However, Kang et al

Although some peptides may reach the small intestine unchanged, many of them will likely be broken down during digestion