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Distant metastasis and progression: Breast cancer metastasis is a complex, multicellular, and highly regulated process involving local invasion of primary tumor cells, epithelial-to-mesenchymal transition, invasion into the bloodstream, survival of tumor cells in the circulatory system, and colonization of secondary distant sites

cryoprotectants or osmolarity regulators Definitions This document relates to preserving biological materials, and more particularly to materials and methods for cold or cryo-preserving organs, tissues, and cells while reducing or minimizing damage to same

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Recent work has identified the endocannabinoid system (ECS) as a key mediator in lipotoxicity, with Cannabinoid receptor type 1 (CB1) activation promoting lipogenesis and inflammation (211)

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