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Mitochondrial damage-associated molecular patterns: from inflammatory signaling to human diseases

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Restoration of effective cell-mediated immune responses has been explored in different Immunotherapeutic approaches

Comparison (C) focused on reproductive health and fertility, and outcomes (O) were assessed to evaluate the improvements of these interventions

Among the 38 hits from the screen, we selected the 15 with a stronger senolytic effect on etoposide-treated SK-MEL-103 cells and, taking advantage of inhibitors of apoptosis (emricasan) or ferroptosis (liproxstatin 1), assessed their mode of action (Fig