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Description

Small molecules targeting lipid metabolism: The antitumor agent sorafenib, in the presence of ACSL4, activates ferroptosis by directly affecting lipid ROS generation pathways (121)

Patients inject once daily, before sleep, at least 2 hours after their last meal

doi:10.1016/j.tem.2022.08.001 Mancini, Antonio et al

doi: 10.1200/JCO.2021.39.15_suppl.LBA2 252 YangYQuSLiJHuCXuMLiWet al

International guidelines in 2021 require the treatment of CSU to be upgraded from second-generation H1-antihistamines (sgAHs) to omalizumab and cyclosporine (214)