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Together with this lagging strand-associated pathway, other key replisome components in leading or lagging strand such as PCNA and its loader RFC-Ctf18, MCM, Ctf4 cooperate for efficient Sororin recruitment through SMC3 acetylation

In RA, a five-fold increase in the production of mitochondrial ROS was reported, so it has been shown that oxidative stress is a hallmark of this disease [11,12,13]

The E3 ubiquitin ligase activity of RING1B is not essential for early mouse development

10.1016/j.nut.2011.11.008 48

Niu Z, Sun P, Zafereo ME , Liu H, Wei P, Wu J, Gross ND, Shete S, Wei Q, Zheng G, Sikora AG, Calin GA, Li G