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It found that the infusion extract and the highest concentration of the alkaloid extract were able to stop microglial cells from producing two powerful pro-inflammatory cytokines TNF-a and IL6, as well as caspases 1 and 3

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J Clin Investig 122:28712883 Hu Z, Lausted C, Yoo H, Yan X, Brightman A, Chen J, Wang W, Bu X, Hood L (2014) Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity

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Campagna R, Mateuszuk , Wojnar-Lason K, Kaczar P, Tworzydo A, Kij A, Bujok R, Mlynarski J, Wang Y, Sartini D (2021a) Nicotinamide N-methyltransferase in endothelium protects against oxidant stress-induced endothelial injury