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two of these studies specifically examined the category of artificial sweeteners other than saccharin (Gallus et al., 2007

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For instance, inhibition of MCT1 disrupts lactate homeostasis and impairs both glycolytic flux and GSH biosynthesis in MYC-driven cancer, resulting in reduced glucose uptake and depletion of ATP, NADPH and GSH (50)

Other associated genes include TOLLIP, DSP, and AKAP13, which influence immune responses, epithelial stability, and tissue remodeling [23,24,25]

However, the measurement of the ratio of [GSH]:[GSSG] in an intracellular organelle is fraught with technical difficulties