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They utilized dark pretreatment and found that the expression of both MpGSTZ1 and MpGSTU2 remained unchanged following transfer to the darkness, whereas the expression of MpGSTU1 and MpGSTF1 decreased by ~50 and 75%, respectively, when plants were placed in the dark for 2 h (Dean et al., 2003)

sativum fruit extract NO Nitric oxide iNOS Inducible nitric oxide synthase COX-2 Cyclooxygenase-2 ER Endoplasmic reticulum UPR Unfolded protein response MANF Mesencephalic astrocyte-derived neurotrophic factor APS Astragalus polysaccharides AS-IV Astragaloside IV GCLC Glutathione cysteine ligase catalytic subunit GCLM Glutathione cysteine ligase modifier subunit LPAR Lysophosphatidic acid receptor LPA Lysophosphatidic acid GTD Gastrodin GEP Gastrodia polysaccharides VMAT2 Vesicular monoamine transporter 2 GEP Gastrodia polysaccharides SCFA Short-chain fatty acid GSSG Glutathione disulfide DAH Dysfunction in dopamine homeostasis GRb1 Ginsenoside Rb1 Agp Andrographolide Ech Echinacoside CB Corynoxine B Cur Curcumin Mod Morroniside Sal Salidroside GRg1 Ginsenoside Rg1 GRg3 Ginsenoside Rg3 Author Contributions All authors contributed to the study conception and design

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Structural characterization, antioxidant activity, and biomedical application of Astragalus polysaccharide degradation products