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A chemical mechanism for the inhibition of SARS-CoV-2 Mpro cysteine-145 by ebselen and its derivatives has been published (Reference Amporndanai, Meng and Shang81)

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Lung-on-chip also revealed to be an ideal platform for infectious diseases study, where the complex and dynamic device microenvironment generates essential data not achievable with classic 2D in vitro models (130, 131)