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Functional studies provide tangible data: When GF mice are administered recombinant IGF-1 (to recapitulate the growth-promoting effect of microbial colonization), this has a substantial beneficial effect on body development and femur elongation

The carrageenan-induced increase in the levels of the cytokine-inducible nitric oxide synthase, IL-1, and IL-6 was abrogated following treatment with CBC