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Although the study involved a large sample size, it is a cross-sectional study and from a single center

For a long time, calcitriol or alfacalcidol was the preferred therapy in uremic patients with high to very high plasma intact PTH values and normal to moderately elevated plasma calcium levels, when plasma phosphate did not exceed recommended levels, namely 1.5 mmol/L for CKD stages 3-4 and 1.8 mmol/L for CKD stage 5, according to the K/DOQI guidelines of 2003 (275)

doi: 10.3389/fendo.2024.1390013 Received 22 February 2024 Accepted 22 July 2024 Published 02 August 2024 Volume 15 - 2024 Edited by Katja Teerds, Wageningen University and Research, Netherlands Reviewed by Wen-Xiang Liu, Inner Mongolia University, China Avi Lerner, Imperial College London, United Kingdom Updates Copyright 2024 Wang, Zhang, Ma, Xu, Zhao, Zhang, Li, Zhou and Zheng

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BPC-157 is one of very few peptides that remains stable in human gastric juice, giving it meaningful oral bioavailability in preclinical models