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The evidence base for DSIP in humans is limited

In an 8-week trial with trained lifters, the full-body group lost notably more fat across multiple regions, per DXA scans

When treating metabolic disorders with IGF-1, phase II trials until now conducted by Clemmons et al

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However, for orthobiologic injections, the flare-up and loss of function are much less, so the focus is on fixing the biomechanical problems that caused the orthopedic problem