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The regression curve for GSH and GSSG was the basis to calculate the content of reduced glutathione and oxidized glutathione in the biological samples (Fig

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ROS can potentially activate the PI3K/Akt pathway by oxidizing and inhibiting phosphatases that generally inhibit Akt activation

On the other hand, research comparing tocotrienols and tocopherols suggests that tocotrienols might require lower dosages for effective neuroprotection compared to tocopherols, primarily due to their enhanced ability to cross the bloodbrain barrier and their greater antioxidative potential against neuroinflammatory markers [90,91,92]