Most carotenoids, including beta-carotene, lutein, zeaxanthin, and lycopene, exude beautiful orange, red, and yellow colors, which is why we often find these nutrients in produce like tomatoes, carrots, and pumpkins
doi: 10.1007/BF01709751 16 LambdenSLaterrePFLevyMMFrancoisB
Cell viability assay of MIA PaCa-2 and PANC-1 cells after knockdown of TXNDC12, (B)
Abbreviations I/R: Ischemiareperfusion IRI: Ischemiareperfusion injury OIRIs: Organ ischemiareperfusion injuries RCD: Regulated cell death ROS: Reactive oxygen species PUFA: Polyunsaturated fatty acid LOX: Lipoxygenase Lipid-OOH: Lipid peroxides TF: Transferrin TfR1: Transferrin receptor protein-1 STEAP3: Prostate six-transmembrane epithelial antigen 3 DMT1: Divalent metal transporter 1 LIP: Labile iron pool PCBP1: Poly-(rC)-binding protein 1 PCBP2: Poly-(rC)-binding protein 2 FPN1: Ferroportin SLC7A11: Solute carrier family 7 member 11 xCT: Cysteine/glutamate transporter SLC3A2: Solute carrier family 3 member 2 4F2hc: 4F2 heavy chain GSH: Glutathione OH: Hydroxyl radicals O2 : Superoxide anions H2O2: Hydrogen peroxide GPX: Glutathione peroxidases Lipid-OH: Lipid alcohol GSSG: Glutathione disulfide GR: Glutathione reductase NADPH: Nicotinamide-adenine dinucleotide phosphate FA: Fatty acid PL: Phospholipid SFA: Saturated fatty acid MUFA: Monounsaturated fatty acid PUFA: Polyunsaturated fatty acid ACSL4: Acyl-CoA synthetase long-chain family member-4 LPCAT3: Lysophosphatidylcholine acyltransferase-3 PE: Phosphatidylethanolamine AA: Arachidonic acid AdA: Adrenic acid MDA: Malondialdehyde 4-HNE: 4-Hydroxy-2-nonenal IIRI: Intestinal ischemiareperfusion injury CAT: Capsiate TRPV1: Transient receptor potential cation channel subfamily V member 1 H/R: Hypoxia-reoxygenation Sp1: Special protein 1 APG: Apigenin-7-O--D-(-6-p-coumaroyl)-glucopyranoside HO-1: Heme oxygenase 1 MAO-B: Monoamine oxidase b ALI: Acute lung injury Nrf2: Nuclear factor erythroid 2-related factor 2 ARE: Antioxidant reaction element Nrf2 / : Nuclear factor erythroid 2-related factor 2 gene knockout TERT: Telomerase reverse transcriptase STAT3: Signal transducer and activator of transcription 3 BCAA: Branched-chain amino acids L-BAIBA: L--aminoisobutyric acid LIRI: Lung ischemiareperfusion injury MIRI: Myocardial ischemiareperfusion injury USP7: Ubiquitin-specific protease 7 FTH1: Ferritin heavy chain 1 ALOX15: Arachidonate 15-lipoxygenase 15-HpETE: 15-Hydroperoxyeicosatetraenoic acid Pgc1: Peroxisome proliferator-activated receptor gamma coactivator 1-alpha RNF34: Ubiquitin ligase ring finger protein 34 KMT2B: Lysine-specific methyltransferase 2B RFK: Riboflavin kinase TNF: Tumor necrosis factor NOX2: Nicotinamide-adenine dinucleotide phosphate oxidase 2 ATF3: Activating transcription factor 3 FANCD2: Fanconi anemia complementation group D2 RIRI: Renal ischemiareperfusion injury AKI: Acute kidney injury Dex: Dexmedetomidine 2-AR: 2-Adrenergic receptor OGD/R: Oxygenglucose deprivation and reoxygenation USC: Urine-derived stem cell USC-Exo: Urine-derived stem cell-derived exosome TUG1: Taurine-upregulated gene 1 SRSF1: Serine/arginine splicing factor 1 IRE1: Inositol requiring enzyme 1 JNK: C-Jun NH2-terminal kinases CCL2: Chemokine (CC motif) ligand 2 CCL7: Chemokine (CC motif) ligand 7 HIRI: Hepatic ischemiareperfusion injury LT: Liver transplantation Ptgs2: Prostaglandin-endoperoxide synthase 2 TMEM16A: Transmembrane member 16A MSC-Exo: Mesenchymal stem cell-derived exosome miR: MicroRNA BMMSC: Bone marrow mesenchymal stem cell IREB2: Iron response element-binding protein 2 MCTR1: Maresin conjugate 1 in tissue regeneration DMF: Dimethyl fumarate ME1: Malic enzyme 1 PTEN: Phosphatase and tensin homolog mTOR: Mechanistic target of rapamycin SREBP1: Sterol regulatory element-binding protein 1 IS: Ischemic stroke CIRI: Cerebral ischemiareperfusion injury NQO1: Quinone oxidoreductase 1 MCAO/R: Middle cerebral artery occlusion and reperfusion ELA: Elabela APJ: Apelin receptor NLRP3: Nucleotide-binding oligomerization domain-like receptor pyrin domain-containing 3 FACL4: Fatty acid-CoA ligase 4 PGE2: Prostaglandin E2 COX: Cyclooxygenase NCOA4: Nuclear receptor coactivator 4 SOD: Superoxide dismutase LDH: Lactate dehydrogenase LPO: Lipid peroxidase HETE: Hydroxyeicosatetraenoic acid ALT: Alanine aminotransferase AST: Aspartate aminotransferase HNF4: Hepatocyte nuclear factor-4 References Dixon SJ, Lemberg KM, Lamprecht MR, Skouta R, Zaitsev EM, Gleason CE, Patel DN, Bauer AJ, Cantley AM, Yang WS, Morrison B, Stockwell BR (2012) Ferroptosis: an iron-dependent form of nonapoptotic cell death
Y., Wong, S
