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Finally, in the co-cultured model, we treated H69 cells in the insert with AA in the presence or absence of a STAT3 activator(Colivelin)and found STAT3 activation of H69 cells suppressed the THP1 mRNA expression of M1 cytokines and induced THP1 M2 gene expression

10 of 14 trials included caffeine

Alternative therapeutic thoughts in APAP hepatotoxicity Targeting APAP hepatotoxicity at the molecular level as an alternative to NAC therapy has been the goal of many research groups