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Description

A population-based study of Graves' disease in Danish twins

J.Jr.CrewsD

Secondary end points included the AUC inf for dextromethorphan and C max , t 1/2 , t max , and CL/ F for dextromethorphan, midazolam, and their respective metabolites

As a result, targeting a single metabolic pathway may not lead to sustained therapeutic responses, as compensatory mechanisms can activate other pathways, undermining the treatments efficacy