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In addition, pregabalin prevents the alpha2-delta subunit from being trafficked from the dorsal root ganglia to the spinal dorsal horn, which may also contribute to the mechanism of action

Jaundice, right-upper quadrant pain, nausea, vomiting, hepatomegaly and encephalopathy indicate high levels of APAP ingestion, and thus when these symptoms are observed the patients APAP level should be checked