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The recommended dose of pemetrexed for injection for treatment of recurrent non-squamous NSCLC in patients with a creatinine clearance (calculated by Cockcroft-Gault equation) of 45 mL/min or greater is 500 mg/m 2 as an intravenous infusion over 10 minutes on Day 1 of each 21-day cycle until disease progression or unacceptable toxicity

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This difference might reflect variations in injection training and technique outside of controlled trial settings

Light action spectrum on oxidative stress and mitochondrial damage in A2E-loaded retinal pigment epithelium cells