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162 In addition, activated notch may affect islet architecture through Ephrin A5 (EFNA5) which is increased in T2D 163 (Fig

Additionally, miR-221 and miR-222 expression increases during early atherosclerosis, negatively correlating with eNOS signaling [89]

This aim is delayed due to participant recruitment

These radicals inflict severe cellular damage by disrupting membranes, proteins, and DNA, ultimately causing myocardial cell injury and death (96)

166,167 Muscle-enriched miR-486 was induced by exercise and was necessary to mediate the beneficial effect of exercise in reducing I/R injury and myocardial apoptosis through targeting PTEN and FoxO1