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Senile plaques (extracellular depositions) and neuronal tangles (intracellular accumulation of misphosphorylated tau protein), are the main histopathological hallmarks of the AD, critical for post-mortem diagnosis

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CSF: T1 = 3,817 ms, and T2 = 503 ms 3638

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A 161A , 30053011 (2013)

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For intracellular staining, the cells were then fixed and permeabilised using eBioscience Foxp3/Transcription Factor Staining Buffer Set (#00-5523-00, Invitrogen) according to the manufacturers instructions

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