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In these lines, a recent study in a methylazoxymethanol acetate rat model of schizophrenia showed that resting oxidative metabolism, as measured by 1 H-[ 13 C] MRS with administration of [1,6- 13 C]glucose, was reduced in the orbitofrontal cortex, increased in the visual cortex, and unaltered in the somatosensory cortex and dorsal hippocampus, when compared to controls [134]

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