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These observations suggest that hemoglobin serves as more than just a biomarker of oxygenation

Besides reducing -amyloid load, treatment with DFMO coerced astrocytes into a neuroprotective state

PPAR Regulation of Inflammatory Signaling in CNS Diseases Despite being an immune privileged site, the central nervous system (CNS) often exhibits inflammation in various CNS diseases

In addition to their roles in modulating the immune system, other functions have been attributed to exosomal cargo including enhanced vascular leakiness, fibronectin deposition, and delivery of soluble factors that are involved in ECM remodeling to support formation of a metastatic niche for tumor cells, including melanomas ( Figure 2 ) (104, 109112)