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The pathogenesis of HCC driven by NASH and the preventive and therapeutic effects of natural products

201,202 Administration of the PRMT6 inhibitor EPZO20411 can inhibit the arginine methylation of chromatin condensation regulator 1 (RCC1), block the tyrosine kinase 2 (CK2) -PRMT6-RCC1 signaling axis, inhibit the proliferation of glioblastoma stem cells (GSCs) and increase their sensitivity to radiotherapy