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For instance, researchers covalently conjugated FN to 4-arm PEG using a Michael-type addition reaction to fabricate hydrogels for delivering VEGF and BMP-2, and the findings demonstrated sustained release of BMP-2 and VEGF for osteogenesis and angiogenesis [191]

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The brain is particularly susceptible to oxidative stress given its limited antioxidant enzymatic capacity to counteract reactive oxygen species production (Fisher-Wellman and Bloomer, 2009), habitual RT has been associated with a reduction in markers of oxidative stress at rest, with the bulk of evidence coming from animal models

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