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PET imaging abnormalities can be seen decades before symptom onset [34]

In the peroxidatic part, one molecule of H 2 O 2 reacts with the selenol group from Sec in GPx, producing a selenenic acid at the active site [47, 66]

However, sleep deprivation can also happen for medical reasons

An analysis of this relationship was incorporated into a Bayesian error regularization procedure (described in the Methods section) to improve our error estimates