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doi: 10.1038/s41598-017-01179-4 203 Van LaerKButsLFoloppeNVertommenDVan BelleKWahniKet al

Gut metabolite Urolithin A inhibits Osteoclastogenesis and senile osteoporosis by enhancing the autophagy capacity of bone marrow macrophages

Hwangpo TA, Jordan D, Premsiriut P, Jayamaran G, Licht JD , Iyengar R, Neves SR

Lactate leads to overactivation of Drp1-related mitochondrial fission and inhibition of PINK/Parkin-mediated mitophagy through the PARP1/POLG/UCP2 axis [123]