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An ex vivo drug susceptibility assay was used to define the CQ susceptibility phenotype of each isolate and isolates were preserved for in-depth omics characterization

References Smith, J

GHR/ mice have a 3040% reduction in body size [160,162164] as well as a 65% reduction in tibial elongation rate [165,166] and decreased chondrocyte proliferation and hypertrophy [162]

Few studies suggest that IGF-1 is upregulated in damaged muscle tissue and is associated with chronic pain conditions such as endometriosis, bone cancer, and orofacial pain 20,21