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J Clin Invest (2017) 127:288191

PMID: 31 SunHZhangJQiHJiangDHuCMaoCet al

Mottas I, Bekdemir A, Cereghetti A, Spagnuolo L, Yang YS, Mller M, Irvine DJ, Stellacci F, Bourquin C

In the original 2015 Cell Metabolism paper, MOTS-c activated AMPK, improved insulin sensitivity in diet-induced obese mice, and reduced age-related insulin resistance in older animals [2]