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By combining free iron in a complex, DFO protects Fe 3+ from reduction and avoids the formation of ROS through Fenton reaction ( in ex vivo perfused hearts (Kobayashi et al., 2018)

The same considerations that make any hormonal intervention require clinical supervision apply here: the need for baseline laboratory assessment, individualized dosing, and ongoing monitoring to detect side effects before they become clinical problems

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It is expected that the aforementioned research methodology can provide better opportunities for the development of novel lightening agents that are effective and safe for use in the clinical and cosmetic industries

In addition, neither placebo nor the nitroglycerine patch improved the flow resistance in the uterine artery [22]