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Delayed gastric emptying may affect the absorption of some oral medicines, particularly those with a narrow therapeutic index (for example, levothyroxine or certain anticoagulants), and may reduce overall nutritional intake during active weight loss

And the foundational paper was retracted

When you swallow a standard capsule of glutathione, the harsh acids in your stomach often break the molecule apart before it ever reaches your small intestine

Int Res J Pharm 3:139148 Farzaei MH, Bahramsoltani R, Abbasabadi Z, Braidy N, Nabavi SM (2019) Role of green tea catechins in prevention of age-related cognitive decline: pharmacological targets and clinical perspective

[17] [18] Women of childbearing potential should inform their healthcare provider if they are taking ALA or planning to start it, and pregnant patients should only use alpha-lipoic acid if it is prescribed by a physician who has judged that the expected benefits outweigh the possible risks