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Clinically, PCOS patients exhibit reduced gut microbial -diversity, an elevated Bacteroidetes-to-Firmicutes ratio, and decreased abundance of beneficial bacteria such as Akkermansia muciniphila

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Interestingly, AIF seems a key node in the p53-mediated RCD network, as apoptosis, parthanatos, and programmed necrosis could be connected with one another through this mitochondrial protein [53, 54] (Fig

GST's other enzymatic activities In addition to the classical conjugation reactions, GSTs have a role in several other catalytic functions