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While GHK-Cu treatment alone did not cause any visible histological changes or toxicity, pretreatment with GHK-Cu markedly attenuated these pathological alterations, resulting in a significantly reduced lung injury score compared to the LPS-only group

This cloned library included the 635 regulatory genes identified at a 10% FDR from the genome-wide screen, as well as 100 manually curated ferroptotic genes of interest, and maintained excellent diversity (Extended Data Fig

Confirmatory secondary endpoints included additional HbA 1c comparisons and relative change in bodyweight (%) from baseline to week 68

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When PUFAs are bound to cell membranes, they can undergo peroxidation as well as ferroptosis