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Major Modifications As outlined in the 2022 Summary of Major Modifications and Explanatory Notes, the Major Modifications for 2022 include the following: 1

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Accordingly, because these CPT codes 99446, 99447, 99448, 99449, 99451, and 99452 recognize and reflect medical practice trends in primary care and patient-centered care, we continue to believe they should be included in the definition of primary care services used for purposes of assignment

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Advances in the epidemiology, pathogenesis and management of diabetic peripheral neuropathy