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As the protective effect of Nrf2 against oxidative stress lies in the Nrf2-dependent induction of antioxidants, all studies, therefore, focused also on measuring the expression of several antioxidant genes (e.g., HO-1, NQO1, etc.)

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Effect of green tea powder supplementation on inflammation gene expression in the heart of ISO-administered rats The transcription levels of six genes related to inflammation, including interleukin-1 (IL-1), interleukin-6 (IL-6), nuclear factor kappa B (NF-B), transforming growth factor beta-1 (TGF-), tumor necrosis factor-alpha (TNF-), and inducible nitric oxide synthase (iNOS), were assessed in the left ventricle of the heart (Fig

1068 Metformin also reduces insulin-like growth factor (IGF) signaling pathway activity, decreases glucose absorption, and promotes glucose breakdown, thus reducing energy supply and growth of cancer cells

Lymphoma Myeloma Leuk 17, Supplement 2 (SOHO 2017):S273, 2017